Marking the eighth Christmas season of his pontificate, the 85-year-old read his "Urbi et Orbi" (to the city and the world) message to tens of thousands of people in St Peter's Square and to millions of others watching around the world.
Delivering Christmas greetings in 65 languages, Benedict used the Biblical analogy of the "good soil" to underscore his view that the hope represented by Christmas should never die, even in the most dire situations.
"This good earth exists, and today too, in 2012, from this earth truth has sprung up! Consequently, there is hope in the world, a hope in which we can trust, even at the most difficult times and in the most difficult situations," he said.
In his virtual tour of the some of the world's trouble spots, he reserved his toughest words for Syria, Nigeria and Mali.
Pope Benedict also held out a Christmas olive branch to the new government in China, asking is members to "esteem the contributions of religions". China does not allow its Catholics to recognise the pope's authority, forcing them to be members of a parallel state-backed Church.